Two Positions as doctoral student in Economic History at the Department of Economic History. Reference number SU 617-2291-10. Deadline for applications: October 15, 2010.
Subject and project description
The department of Economic History offers two positions in the doctoral studies program/Third Level programmes. Within the doctoral studies program it is required that the student formulate and conduct a PhD project and take the required courses, according to an individual study-plan.
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Admitted PhD students will receive funding for at least three years including support to visit international conferences and specialized workshops.
The program offers cutting-edge education in the fields of Neurobiology, Vascular Biology, Immunology and Inflammation Research and integrates basic, applied, and clinical sciences, as well as a huge spectrum of experimantal techniques.
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In general, programs perform analysis on user input in order to generate output tailored to user needs. In particular, compilers perform program analyses to check for correctness, provide good feedback on programming errors, and improve performance of generated programs. Such analyses are costly to perform, and at the same time, must often be done in short periods of time, for example because of its use in an interactive editing environment. Extensive analyses and fast execution of such analyses thus are two conflicting requirements.
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The duration of the Mamaself Masters course is two years (120 ECTS credits). The academic programme is split into two years with 60 ECTS credits for each. The language of instruction and examination is English. The student will stay one year in one institution and a second second in another institution. It is not possible to stay the two years at the same site in Munich. The second year will be split in two semesters : the first one at a university, the second one is dedicated to the Master thesis project and can be conducted at another university or at Large Scale Facilities.
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How exposure to synthetic estrogen and common pharmaceuticals affects activation of hormone receptors and biotransformation processes in brown trout. The goal for this project is to study how pharmaceutically active compounds (PACs), which today are readily detected in various natural environments, impact biological processes in brown trout (Salmo trutta). We want to investigate if exposure to synthetic (human) estrogen activates fishes? hormone receptor genes and biotransformation genes. We also want to know if/how the activation changes if we simultaneously expose them to another PAC. Questions include: is activation by estrogen different when in the presence of common pain relievers, anti-inflammatory drugs or anti-depressants (diclofenac, ibuprofen and paracetamol, diazepam)? Identification and screening of genetic polymorphisms that mediate specific responses to synthetic pharmaceuticals and estrogens will be used to identify high- and low risk genotypes in studied individuals.
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The doctoral candidate programme amounts to 240 credits, the equivalent of four years of full time studies. The programme formally ends with the doctoral candidate publically defending her/his published doctoral thesis. The holder of limited tenure doctoral position has as her/his primary obligation to successfully fulfill her/his third cycle education ending with an approved Ph.D. thesis. Regulations for limited tenure employment as a doctoral student are found in Higher Education Ordinance (chapter 5, 1-7§§). Only those persons who have been formally accepted to doctoral studies can be eligibile for limited tenure employment as a doctoral student.
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Biochemical characterization of antibody-based radioconjugates for SPECT/PET/CT imaging of prostate cancer. The monoclonal antibodies and their derivatives are produced in collaboration with several research groups in New York, Åbo and Malmö. These antibodies bind specifically to human kallikrein 2 (hK2), which are abundantly expressed in prostatic tissue. The purpose of this project is to target the hK2 protein with radiolabelled antibodies and/or antibody fragments in order to detect metastases and with suitable radioisotopes to treat tumours.
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Modelling of structure-activity relationships with the help of quantum chemical and statistical mechanical methods applied to binding of ligands to biological receptors. The work will be carried out in cooperation with AstraZeneca.
Eligibility/Entry Requirements
Basic entry requirements for PhD studies are: a degree at advanced level, courses to an extent of at least 240 credits, of which at least 60 at advanced level, or corresponding proficiencies aquired in Sweden or elsewhere.
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